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・ Actinoposthiidae
・ Actinoprosopa maris
・ Actinoptera
・ Actinopteri
・ Actinopterygii
・ Actinopteryx
・ Actinoptilum
・ Actinoptilum molle
・ Actinopus
・ Actinopyga
・ Actinoquinol
・ Actinor
・ Actiniidae
・ Actinin
・ Actinin alpha 4
Actinin, alpha 1
・ Actinin, alpha 2
・ Actinioidea
・ Actiniopteris
・ Actiniopteris radiata
・ Actinism
・ Actinistia
・ Actinium
・ Actinium(III) oxide
・ Actino-pnp RNA motif
・ Actinoallomurus
・ Actinoalloteichus
・ Actinobacillosis
・ Actinobacillus
・ Actinobacillus pleuropneumoniae


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Actinin, alpha 1 : ウィキペディア英語版
Actinin, alpha 1

Alpha-actinin-1 is a protein that in humans is encoded by the ''ACTN1'' gene.
== Function ==

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=87 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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